The researchers need women who have not had breast cancer who live in or near Austin, Texas to help gain a better understanding of brain function in women who have not had cancer. The research team is looking for volunteers age 40 to 75 who have no major medical or psychiatric conditions.
The effects that breast cancer and its treatments have on brain health are not well understood. To address this problem, researchers at the University of Texas in Austin want to learn more about brain function in healthy women. This will allow them to have a baseline to compare the brain function of women with breast cancer who have been treated with chemotherapy. To study brain function, the researchers will use paper and computerized tests and brain MRI scans.
The purpose of this study is to evaluate brain function in healthy women and in women who have been treated with chemotherapy for breast cancer.
If you sign up to be one of the women without breast cancer in the Predicting Brain Health After Chemotherapy Using Artificial Intelligence study, the research team will call you to ask questions about your medical history to determine if you are a good fit. If you are eligible to participate, the team will schedule your first research appointment and send an informed consent form for your review.
During your first visit, the researcher will review the consent form in detail, allowing you to ask any questions. If you decide to participate, you will visit the University of Texas in Austin for two visits. Each visit will be 2.5 hours. The first visit will occur right after you enroll in the study. The second visit will be about 18 months later. During these visits, the trained research staff will have you take tests that measure attention, processing speed, memory, and language skills; complete questionnaires on mood, distress, energy, pain, sleep and other symptoms; and complete a brain MRI scan. MRI is a non-invasive way of taking pictures of the brain. It does not involve any injections, radiation or other harmful effects. The research team also will collect a sample of your saliva and a sample of your blood.