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Closed Projects

Since October 2008, we have supported more than 145 studies, connecting over 106,000 volunteers with innovative research around the world. These research projects have studied everything from our microbiota to novel breast cancer genes. We have made a point to partner with researchers who are asking important questions that may help eradicate breast cancer.

While these research studies are always different, there is one common factor: our dedicated Army of Women members. With their help, the following supported studies completed enrollment:

This study at City of Hope in Duarte, Calif., is investigating the effect two years of low-dose tamoxifen has on breast density and other biological markers (biomarkers) associated with increased breast cancer risk in women who had been diagnosed and treated with chest or axilla radiation before the age of 40 for a cancer other than breast cancer. The study is also measuring the safety and tolerability of tamoxifen at the lower dose. The researchers wanted to enroll up to 230 volunteers from various cities around the US and reached out to the Army of Women (AOW) to supplement their other recruitment sources. The Call to Action for this study was sent to AOW members on May 2, 2012, and the researchers closed enrollment on March 19, 2015. The AOW provided them with 13 women who were interested in enrolling in the study.

Date closed: March 19, 2015

The purpose of this study is to examine the patterns of breast density (the non-fatty portion of breast tissue) among African immigrant and African-American women living in the United States, and to find out factors that affect the amount of breast density in women. The researchers wanted to enroll 300 women to participate in this study.

Date closed: March 17, 2015

This study at City of Hope in Duarte, Calif., in collaboration with the African American Breast Cancer Coalition, is evaluating the impact of a peer navigator program on helping African-American breast cancer survivors obtain and follow a survivorship care plan. A survivorship care plan consists of two components: a treatment summary describing the cancer diagnosis, history, stage, and primary treatments received; and a follow-up care plan that includes information on recovering from treatment, ways to maintain good health, and recommendations for care. The researchers needed to enroll up to 120 African-American volunteers in the Los Angeles area who were less than a year out from having completed surgery, radiation and/or chemotherapy. They used a variety of recruitment methods, including the Army of Women (AOW). The Call to Action for this study was sent to AOW members on April 25, 2012. The researchers closed enrollment on Jan. 30, 2015, after the AOW provided them with 10 women who were interested in enrolling in the study.

Date closed: January 30, 2015

This study was initiated in November 2011 at University of North Dakota School of Medicine & Health Sciences, Grand Forks and Fargo, and was then put on hold in June 2012 when the Principal Investigator moved to University of Texas Health Sciences Center in Tyler. The study was re-opened in September 2013. The study investigated nipple aspirate fluid and blood to determine if inflammation biomarkers are: higher in breast fluid than in the circulating blood; higher in obese and overweight women compared with normal weight women; and more variable through the menstrual cycle of premenopausal women compared to postmenopausal women. The researchers wanted to enroll up to 42 volunteers, first in the Grand Forks and Fargo area, and then the Tyler area. They turned to the Army of Women (AOW) for recruitment. The Call to Action for this study was sent to AOW members on Nov. 8, 2011. Information regarding the new study site was shared with AOW members in September 2013. The researchers closed enrollment on Jan. 30, 2015, after the Army of Women provided them with 45 women who were interested in enrolling in the study.

Date closed: January 30, 2015

This study at Tufts University in Boston is analyzing breast tissue samples from women without breast cancer. The researchers wanted to compare tissue from women who have or have not given birth. They are studying the stroma, the breast tissue that supports the breast ducts. They are also investigating whether the age a woman becomes pregnant, the number of pregnancies she has had, and whether or not she has breast-fed has an effect on the stroma. The researchers turned to the Army of Women (AOW) to enroll up to 85 volunteers in the Boston area. The Call to Action for this study was sent to AOW members on Jan. 1, 2011. The researchers closed enrollment on Nov. 10, 2014, after the AOW provided them with 116 women who were interested in enrolling in the study.

Date closed: November 10, 2014

This study at the University of Massachusetts, Amherst, is analyzing epigenetic differences found in breast milk donated by women who have a breast biopsy that is either normal, abnormal, or shows signs of cancer. Learning more about these epigenetic differences may eventually help researchers develop a way to provide women with information about their breast cancer risk. The researchers originally wanted to enroll up to 250 volunteers from anywhere in the US. The Call to Action for this study was sent to Army of Women (AOW) members on Nov. 17, 2008. The research team expanded their study in 2011 to increase participant diversity, specifically recruiting racial/ethnic minorities. The researchers closed enrollment on Nov. 2, 2014. In total, the AOW provided them with a diverse group of 394 women who were interested in enrolling in the study.

Research Webinar:
The MILK Study

Date closed: November 2, 2014

This study at Georgetown University in Washington, DC, is investigating how women taking hormonal therapies for breast cancer treatment feel about their medications. The researchers wanted to enroll up to 300 volunteers from anywhere in the US and reached out to the Army of Women (AOW) to help them complete recruitment. The Call to Action for this study was sent to AOW members on Aug. 20, 2014. The response from the AOW was overwhelming and the researchers increased their enrollment goal due to the positive response. They closed enrollment on Oct. 28, 2014, after the AOW provided them with 1,149 women who were interested in enrolling in the study.

Date closed: October 28, 2014

This study is investigating whether high-dose vitamin D supplements reduce breast density, as seen on mammography. Breast density is associated with breast cancer risk. The researchers wanted to enroll up to 300 volunteers and contacted the Army of Women (AOW) to help with their recruitment efforts. The Call to Action for this study was sent to AOW members on May 15, 2013, and the researchers closed enrollment on Sept. 16, 2014. The AOW provided them with 172 women who were interested in enrolling in the study.

Date closed: September 16, 2014

The purpose of this study at the University of Minnesota is to learn more about the effect that aromatase inhibitors have on a postmenopausal woman’s heart and blood vessels. To study this, the researchers are analyzing the blood vessel elasticity and heart health of three groups: women with breast cancer who have been on an aromatase inhibitor (and are HER2-negative); women with triple negative breast cancer; and healthy women. The researchers wanted to enroll up to 50 volunteers from the Greater St. Paul, Minn., area and they enlisted the Army of Women (AOW) to help support their recruitment efforts. The Call to Action for this study was sent to AOW members on May 7, 2014, and the researchers closed enrollment on Aug. 11, 2014. The AOW provided them with 95 women who were interested in enrolling in the study.e inhibitors will impair vascular relaxation and result in impaired endothelial function as compared to that of two patient populations: healthy postmenopausal women and those with triple negative breast cancer (TNBC) who do not receive aromatase inhibitors.

Resulting Publications:

Date closed: August 11, 2014

This study at the University of Southern California, in Los Angeles, is investigating the effects of Depo Provera, which contains a high dose of a synthetic progestin, on breast tissue. The researchers wanted to enroll 36 volunteers from the Los Angeles area and the Army of Women (AOW) served as one of their multiple recruitment resources. The Call to Action for this study was sent to AOW members on Sept. 15, 2010, and the researchers closed enrollment on July 29, 2014. The AOW provided them with 14 women who were interested in enrolling in the study.

Date closed: July 29, 2014

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