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The following projects are currently open and enrolling volunteers. These studies were evaluated and approved by the research team at Dr. Susan Love Research Foundation and members of our external Scientific Advisory Committee, comprised of researchers, clinicians, and advocates.
If you would like to learn about the studies we recruited for in the past, please click here.
Regular physical activity is beneficial for women who have been diagnosed with breast cancer, potentially reducing the likelihood of recurrence. Studies have also found exercise can help decrease fatigue, improve mood and cognition, and increase sleep quality. However, many women find it difficult to begin or maintain a regular physical activity program.
A research team from UT Southwestern Medical Center is investigating a new way to help breast cancer survivors increase their physical activity — a six-month education program, available in two Texas locations: Dallas (UT Southwestern) and Fort Worth (Moncrief Cancer Institute).
Some people live for many years following a metastatic breast cancer diagnosis. To gain insight into why, researchers want to learn more about the medical history and health habits of women and men living with metastatic breast cancer. If you take part in this study, you will complete an online survey that will ask you questions about diet, exercise, health behaviors and medical care. Some participants who fill out the survey will also be invited to participate in an optional sub-study, which includes a medical record review, a blood or saliva sample, and tumor analysis. Findings from the survey and optional sub-study may help the research team discover how to help people live longer after a diagnosis of metastatic breast cancer.
The purpose of this study is to compare the effects of a tamoxifen pill to tamoxifen (4-OHT) gel on breast cells in women with ER+ DCIS. This study will investigate what effects each treatment has on the DCIS and what side effects each treatment may cause. Prior studies show that the topical gel stays mainly in the breast itself with very little getting into the blood. The eventual goal is to provide women with DCIS with an alternative to oral tamoxifen treatment.
Women receive mixed messages about what type of breast cancer screening they should have and how often they should have mammograms. The WISDOM Study compares the routine, annual mammogram schedule to a personalized screening schedule based on a woman’s individual risk factors. The goal of the study is to determine the best way to use mammograms to improve breast cancer screening while reducing the number of call backs, false alarms, and biopsies for women who do not have breast cancer.
The purpose of this study is to investigate whether using Temodar and Kadcyla together decreases the chance of patients with HER2+ metastatic breast cancer developing new brain metastases. Approximately 18 participants will take part in this study. Participants enrolled in this trial may be eligible to receive compensation for their travel expenses.
This study aims to identify non-genetic factors that cause only one twin in a pair to get breast cancer. This information could help researchers identify ways to help prevent breast cancer from occurring.
This study is designed to identify both signs and symptoms of breast cancer-related lymphedema and genetic factors that predict whether patients are at increased risk for developing lymphedema. The researchers intend to use the results to develop and test new approaches to prevent or reduce the risk of lymphedema developing following breast cancer treatment.
Genetic and non-genetic factors are believed to influence whether a woman with a BRCA1, BRCA2, and/or PALB2 mutation goes on to develop breast and/or ovarian cancer. The study is trying to identify which hormonal, reproductive, and lifestyle factors may increase cancer risk in this high-risk group.
The purpose of this study is to investigate the relationship between your cardiovascular fitness and your body’s immune response, as both may be related to fatigue (tiredness), mood, pain sensitivity, memory, and concentration—known side effects of cancer and its treatments. By learning if people with better cardiovascular fitness have lower inflammation, researchers will be able to discover whether and how regular exercise benefits breast cancer survivors.
The purpose of this study is to see whether neratinib is effective in treating HER2-negative metastatic tumors that have a specific type of genetic mutation (ERBB2). The first part of this study is a preliminary screening. During this part of the study, your tumor tissue will be tested to see if it has the specific mutation the researchers are looking for. If your tumor has the mutation, you will be given more information about the main research study, which is investigating the effectiveness of neratinib.