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Current Projects

 
  
 
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The following projects are currently open and enrolling volunteers. These studies were evaluated and approved by the research team at Dr. Susan Love Research Foundation and members of our external Scientific Advisory Committee, comprised of researchers, clinicians, and advocates.

If you would like to learn about the studies we recruited for in the past, please click here.

  
Researcher: Hinaben Panchal, MD, MPH, and Evan Matros, MD, MMSc, MPH at Memorial Sloan Kettering Cancer Center, New York, NY
Broadcast date: June 22, 2018

All breast cancer patients have many decisions to make as they decide which breast cancer surgery, and other treatments, are right for them. These decisions may be influenced by input from family, friends, and doctors – but what is important to them might not be what matters most to the patients themselves. The purpose of this study is to better understand which factors women and men find most important as they consider different surgical treatment options. The researchers completed enrollment of participants without a breast cancer diagnosis and now need women who had a single or double mastectomy after a breast cancer diagnosis. The researchers will use what they learn to improve how health care providers approach shared decision-making with their breast cancer patients.

Researcher: Mark Burkard, MD, PhD, University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
Broadcast date: May 10, 2018

Some people live for many years following a metastatic breast cancer diagnosis. To gain insight into why, researchers want to learn more about the medical history and health habits of women and men living with metastatic breast cancer. If you take part in this study, you will complete an online survey that will ask you questions about diet, exercise, health behaviors and medical care. Some participants who fill out the survey will also be invited to participate in an optional sub-study, which includes a medical record review, a blood or saliva sample, and tumor analysis. Findings from the survey and optional sub-study may help the research team discover how to help people live longer after a diagnosis of metastatic breast cancer.

Researcher: Seema Khan, MD, Northwestern University, Chicago, IL, Joseph Michael Guenther, MD, St. Elizabeth HealthCare, Edgewood, KY, Amy Degnim, MD, Mayo Clinic, Rochester, MN, Melissa Pilewskie, MD, Memorial Sloan Kettering Cancer Center, New York, NY, E. Shelley Hwang, MD, Duke University, Durham, NC, Stephen Grobmyer, MD, Cleveland Clinic, Cleveland, OH
Broadcast date: February 16, 2018

The purpose of this study is to compare the effects of a tamoxifen pill to tamoxifen (4-OHT) gel on breast cells in women with ER+ DCIS. This study will investigate what effects each treatment has on the DCIS and what side effects each treatment may cause. Prior studies show that the topical gel stays mainly in the breast itself with very little getting into the blood. The eventual goal is to provide women with DCIS with an alternative to oral tamoxifen treatment.

Researcher: Laura Esserman, MD, MBA, University of California, San Francisco, CA and her partners from the Athena Breast Health Network (a collaboration across the five University of California Medical Centers and Sanford Health)
Broadcast date: February 16, 2018

Women receive mixed messages about what type of breast cancer screening they should have and how often they should have mammograms. The WISDOM Study compares the routine, annual mammogram schedule to a personalized screening schedule based on a woman’s individual risk factors. The goal of the study is to determine the best way to use mammograms to improve breast cancer screening while reducing the number of call backs, false alarms, and biopsies for women who do not have breast cancer.

Researcher: Tonia Poteat, PhD, and Lorraine T. Dean, ScD of Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
Broadcast date: January 12, 2018

The purpose of this study is to learn about the best ways to improve access to breast cancer care and treatment for members of the Black LGBQ-SGL community. The research team will enroll up to 30 participants for an in-depth phone interview about identities and healthcare experiences.  

Researcher: Alexandra Zimmer, M.D., at the National Cancer Institute, Bethesda, MD
Broadcast date: September 19, 2017

The purpose of this study is to investigate whether using Temodar and Kadcyla together decreases the chance of patients with HER2+ metastatic breast cancer developing new brain metastases. Approximately 18 participants will take part in this study. Participants enrolled in this trial may be eligible to receive compensation for their travel expenses.

Researcher: Carolyn Westhoff, MD, Columbia University, New York, NY
Broadcast date: August 9, 2017

Researchers at Columbia University need healthy women in the greater New York City area between the ages of 18 and 39 to participate in a study investigating the effects of two medications on breast cell proliferation. The new pill being studied contains Ulipristal Acetate, or UPA. UPA is a selective progesterone-receptor modulator, or SPRM. Like tamoxifen (a selective estrogen receptor modulator, or SERM), UPA interacts with female hormones that affect the breast. Previous studies show that progesterone increases breast cell growth, and UPA may block this increase. The control medication in this study is a low-dose birth control pill that has been used in the U.S. for over 30 years. The research team wants to see if the UPA pill has a different effect on breast cells than currently used low-dose contraceptive pills. Because SPRM’s hormonal interference can block ovulation, UPA is also a potential contraceptive. This research is the first step in learning if an UPA contraceptive could decrease the long-term risk of breast cancer.

The purpose of this phase I clinical trial is to learn how two different medications affect the breast: an estrogen-free selective progesterone-receptor modulator called UPA vs. a low-dose oral contraceptive pill. This study completed recruitment for the low-dose oral contraceptive group. Now, the research team is looking for participants to enroll in the UPA group.

Researcher: Thomas Mack, MD, MPH, University of Southern California, Los Angeles
Broadcast date: July 12, 2017

This study aims to identify non-genetic factors that cause only one twin in a pair to get breast cancer. This information could help researchers identify ways to help prevent breast cancer from occurring.

Researcher: Patricia A. Ganz, MD, Julienne Bower, PhD, and Catherine Crespi, PhD, at University of California, Los Angeles; Ann Partridge, MD, MPH and Hadine Jaffe, MD, MSc at Dana-Farber Cancer Institute; and Antonio Wolff, MD, Katherine Smith, PhD, and Elissa Bantug, MHS, at Johns Hopkins University
Broadcast date: May 3, 2017

The purpose of this study is to see how well two different types of group programs—mindfulness-meditation classes and survivorship education classes—meet the needs of young survivors. Up to 360 women will take part in this study. Three institutions are collaborating on this project: University of California, Los Angeles, Dana-Farber Cancer Institute, and Johns Hopkins University

Researcher: Christine Miaskowski, PhD, RN, University of California, San Francisco
Broadcast date: April 25, 2017

This study is designed to identify both signs and symptoms of breast cancer-related lymphedema and genetic factors that predict whether patients are at increased risk for developing lymphedema. The researchers intend to use the results to develop and test new approaches to prevent or reduce the risk of lymphedema developing following breast cancer treatment.

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